The prime minister has said the "perfect deal" is not on offer and while it involves compromises, British firms will get tariff and quota free access to European markets, freedom of movement will end and the United Kingdom will exit the Common Agricultural Policy and Common Fisheries Policy.
The result of the vote - a defeat by seven with 20 Tory MPs rebelling, including former cabinet ministers Sir Michael Fallon and Justine Greening - is one thing, and a bad introduction to the resumption of the "meaningful vote" debate.
The UK Parliament passed legislation last year stating that the UK would leave the European Union on 29 March - two years after negotiations on its exit began.
May's government suffered a defeat in parliament on Tuesday when lawmakers who oppose leaving without a deal won a vote on creating a new obstacle to a no-deal Brexit.
This is not what her officials tell her: the forecasts are for economic growth to slow after Brexit, meaning there will be less money to go round.
Meanwhile, a cross-party group of pro-EU MPs have backed a new amendment that would require Mrs May to return to the Commons with a new plan within just three days if she loses the meaningful vote.
Asked if he was prepared to resign to stop a no-deal Brexit, Mr Harrington said: "Definitely, I would". Indeed, our data suggests that, far from the Christmas break having softened parliamentary...
Twenty Conservative MPs joined opposition parties in backing a cross-party amendment to the Finance Bill meant to limit the Government's powers to make tax changes in the event of no-deal.
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"The deal that is on the table is the best and the only deal possible", European Commission spokesman Margaritis Schinas said in Brussels, adding that the bloc is "closely" watching Brexit developments in the U.K. Commission President Jean-Claude Juncker plans to speak to May again this week. She postponed a scheduled vote on the deal in December after it became clear she would lose.
Some British ministers also said they hope to set out further reassurances from the European Union that the backstop is only temporary, but so far even this has not been agreed and the pro-Brexiteers feel that the temporary might end up to be indefinite.
For now it seems likely that Number 10's inevitable efforts to leverage this vote to persuade Brexiteers to accept the deal will not work next week at least.
The EU, for its part, has insisted that the withdrawal agreement can not be renegotiated but has made clear the backstop is meant only as a temporary measure of last resort.
"Todayâs trial can not possibly duplicate the reality of 4,000 trucks being held at Manston airport in the event of a no-deal Brexit", the RHA's chief executive Richard Burnett said in a statement.
And she said: "More than ever we need to find the centre, reach across the House and find a majority for what will be agreed".
But anti-Brexit MPs pounced on James' remarks, claiming she had let slip the reality facing ministers.
The DUP's Nigel Dodds told BBC's Newsnight it was "more a social occasion" than a political one.