"U.S. citizens may be subjected to prolonged interrogations and extended detention for reasons related to 'state security, '" the advisory says.
Chinese government officials are saying it's not "convenient" to discuss the alleged national security threats - this while the Huawei CFO is treated like royalty here in comparison.
The advisory also warns about China's use of "exit bans" that would prohibit USA citizens from leaving the country, sometimes keeping them in China for years.
In most cases, USA citizens only become aware of the exit ban when they attempt to depart China.
"China always welcomes foreign citizens, including USA citizens, to visit China, and protects their security and legal rights, including freedom of entry and exit", Foreign Ministry spokesperson Lu Kang told a press briefing.
Updating its travel advisory, the State Department maintained its previous guidance that Americans should exercise increased caution in China. The arrests are widely viewed as Chinese retaliation for Canada's arrest of high-tech executive Meng Wanzhou, Huawei's chief financial officer, by the RCMP in Vancouver at the request of the United States.
December 1: Canadian authorities arrest Meng at Vancouver's airport while she is en route from Hong Kong to Mexico, after an extradition request from the Americans.
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Regarding a very slight number of foreigners suspected of violating laws and committing crimes in China, the Chinese authorities have always impartially handled cases in accordance with the law, and safeguarded their legal rights and interests, he added.
US prosecutors have accused her of misleading banks about transactions linked to Iran, putting the banks at risk of violating sanctions.
December 8: Canada's ambassador to China, John McCallum, is summoned to a meeting with China's assistant foreign minister so the country can register complaints about Meng's arrest.
The Chinese government has not drawn a direct link between the detention of any Canadian and Meng's arrest.
Meanwhile, China's vice premier, with responsibility for the domestic economy, and U.S. Treasury Secretary Steven Mnuchin talk about the ongoing tariff battle between the two countries.
China's foreign ministry says Kovrig and Spavor have been detained on suspicion of "endangering national security".
"Without a doubt, these two Canadian citizens in China violated our country's laws and regulations, and are now undergoing investigation according to procedure", Zhang Jun, China's prosecutor general, said.