However, finding a centre-back in the January transfer window might be hard, and Emery said the injury situation could force the club to examine whether Chambers can be recalled despite being sent on a season-long loan to Fulham in the summer.
Arsenal will be without the injured Rob Holding and Konstantinos Mavropanos while Sokratis Papastathopoulos and Shkodran Mustafi are suspended, meaning the visitors are likely to field an unfamiliar backline at St Mary's.
Arsenal have been handed a boost as midfielder Mesut Özil has returned from an extensive stay on the sidelines following a back injury, Laurent Koscielny will too be in contention to start.
"Mexico is paying for the wall" through savings in new trade deal
President, if you say Mexico is going to pay for the wall through NAFTA , which it certainly won't, then I guess we don't have to. Today, he said that the money saved through his new trade deal with Canada and Mexico will actually help pay for the wall .
Jazz icon Nancy Wilson dies aged 81 after battling illness
During her career, Wilson released almost 70 albums in blues, jazz , R&B, pop and soul. I love the vignette, the plays within the song'.
Mariners, Indians, Rays Getting Together on Encarnacion, Santana, Bauers, Diaz Trade
Philadelphia sent Santana to the rebuilding Mariners this month in a trade that included All-Star shortstop Jean Segura . Highly regarded at 27, his opportunities were limited with the Indians because they already had a talented infield.
"Every young player, we have the responsibility to give them chances, first to train with us and to be demanding with their performances", Emery said when asked about 17-year-old Bukayo Saka who made his full debut on Thursday.
Laurent Koscielny has revealed that he had to learn how to walk again after he underwent achilles surgery in May.
With the hosts having secured top spot last month, there was little riding on the final fixture of the group stage, allowing Emery to select a young team, in anticipation of the Super Sunday clash with Southampton.
Emery has gone with a back three in the league recently but it will be interesting to see if he sticks with it against Southampton as we have plenty of problems at centre-back.
"Nacho Monreal can play in this position. I prefer to use, if we can, a [natural] centre-back". Emery was similarly pleased with his return, saying: "Today is another step for him and for us". It didn't work then, but I think Emery is on to something, and it can always be adjusted at half, as it was against Huddersfield, if things start to go awry, thus saving crucial players for midweek. "But for us it's also very important".