Late Tuesday, an explosive device addressed to former U.S. President Barack Obama was intercepted at his home in Washington D.C. and early Wednesday a similar package was found by the Secret Service addressed to former Secretary of State Hillary Clinton at her home in NY.
The officials said the CNN bomb was crude but operational and appeared similar to explosives sent to former President Barack Obama, Hillary Clinton and billionaire George Soros. Law enforcement officials said they were investigating whether all the devices were sent by the same person or persons.
"The Secret Service has initiated a full scope criminal investigation that will leverage all available federal, state, and local resources to determine the source of the packages and identify those responsible", the agency said in a statement.
There has been no claim of responsibility.
Top Democrat lawmakers Nancy Pelosi and Chuck Schumer accused Trump of condoning "physical violence and dividing Americans".
On Wednesday, Trump spoke out against violence and violent rhetoric.
"Any acts or threats of political violence are an attack on our democracy itself", Trump said. "We've got to come together". And the way to stop that is to turn back the other way, to bring down the temperature, to end any messages about the use of violence against people we disagree with. A Wasserman Schultz district office in South Florida was listed as the return address on the packages, in what current and former investigators said was a feint suggesting particular antipathy on the part of the bomber toward her.
CNN, citing a law enforcement official, was initially told a suspicious package containing a pipe bomb that was addressed to the White House was intercepted at Joint Base Bolling in Washington, DC. Each bore a computer-printed address label and six "Forever" postage stamps.
The mail-bomb scare widened Thursday as law enforcement officials seized three more suspicious packages - two addressed to former Vice President Joe Biden and one to actor Robert De Niro - and said they were similar to crude pipe bombs sent to former President Barack Obama, Hillary Clinton and CNN.
The first inkling that there might be a serial bomber came Wednesday morning when the Secret Service revealed that it had "intercepted two suspicious packages addressed to Secret Service protectees", who were Clinton and Obama.
On Wednesday, the discovery of a suspicious package addressed to NBC and MSNBC correspondent John Brennan found inside CNN's mailroom caused the evacuation of its NY offices.
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An envelope containing white powder was reportedly also found with the device, according to NYPD Commissioner James O'Neill.
The device addressed to Clinton in Westchester County, north of New York City, was found late on Tuesday by a Secret Service employee who screens mail for her, the statement said.
Police officers visited other "locations associated with the Soros family, his businesses", and then when the devices addressed to Clinton and Obama were discovered, "we really widened our outreach", Miller said.
"Whether it's one person or a network, not really sure at this point", NY police chief James O'Neill told CNN, saying he expected those responsible to be identified and arrested within the next few days.
At least one of themwas misaddressed and returned to sender, two law enforcement sources told CNN.
All of the targets are frequently maligned by right-wing critics.
Trump and his aides routinely criticize CNN over its coverage, and the president calls the network an example of "fake news".
CNN chief Jeff Zucker criticized the White House for a "total and complete lack of understanding" of the seriousness of its attacks on the media, as his network's NY bureau was evacuated for five hours Wednesday following the discovery of an explosive device sent there. "Thus far, they have shown no comprehension of that", he said.
It is unclear where exactly the package addressed to Clinton was sent.
Brennan condemned President Donald Trump's often inflammatory rhetoric toward his Democratic opponents and the media, calling the president's behavior "un-American".
President Donald Trump has been briefed on the situation and is receiving "constant updates", Sanders said.