Leicester City refuted United's enquiry, with Maguire a genuine second choice; and Mourinho's frustration on the recent tour of the U.S. was visible to all to see.
The Red Devils have been regularly linked with the Belgian since the start of the transfer window and they now appear to be nearing an agreement with Tottenham Hotspur.
If United seriously want to challenge for honours this season, defence is an area they simply must address - and agreeing a deal for Mina would go a long way towards accomplishing those goals.
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He had been linked with a departure from the club prior to the World Cup, but his performances in Russian Federation have increased his options and seen a variety of sides linked with him.
Having failed to sign Harry Maguire from Leicester City, the Special One turned his attention to the Colombian blocker. The Columbian worldwide has agreed on a 5-year contract with the Toffees with Barcelona accepting an offer in the region of €32 million from the Merseyside club. But apparently the deal has collapsed after Mina's agent, Felipe Russo, angered United officials "by asking for more and different payments".
Jose Mourinho has not hidden his desire to land a new central defender this summer but the club are concerned that both alternatives, Alderweireld and Boateng, are 29 and overpriced.
At Manchester United, the pursuit of a centre-back this summer has been well documented after an underwhelming performance by the defensive unit in the second half of the 2017-18 season.