"The direct consequences of that will be Prime Minister Corbyn".
The timing could not be worse, as Britain faces a fresh diplomatic row with Russian Federation over a nerve agent attack, and ahead of US President Donald Trump's visit this week.
Tanaiste Simon Coveney warned that the Government will take its Brexit lead from Prime Minister Theresa May and stressed that it will be "business as usual" despite the high-profile resignation of Brexit Secretary David Davis.
"If the required 48 members sign what they hope will be her death warrant, they could find that no one is courageous or competent enough to execute it", commentator Charles Moore wrote in the Brexit-backing Daily Telegraph newspaper on Tuesday.
However, the move appears to have reopened divisions within Mrs May's cabinet and despite Mr Davis being swiftly replaced by Dominic Raab and Mr Johnson by Jeremy Hunt, with Matt Hancock taking over as Health Secretary, there are suggestions that the resignations could spark a challenge to the Prime Minister's position.
Under party rules, 48 Tory MPs, 15% of the party's 316-strong representation in the Common, must write to the chairman of the backbench 1922 Committee, Sir Graham Brady, to trigger a no-confidence vote. Europe's most powerful leader, German Chancellor Angela Merkel, arrives in London later on Tuesday.
In his letter of resignation, he described her readiness to accept a "common rulebook" with the European Union in trade on goods and her proposal of "impractical and undeliverable customs arrangements" as being like "sending our vanguard into battle with the white flags fluttering above them". Three junior ministers also quit their posts.
But her administration was thrown into disarray within 48 hours, as first Mr Davis and then Mr Johnson said that they could not commit themselves to promote the plans under the doctrine of collective responsibility.
"I've listened to every possible idea and every possible version of Brexit".
"I wouldn't personalise it, but what struck me when I met him he kept telling us it'll be alright, when I referenced the revenue report and how catastrophic a hard Brexit would be, he simply said that we must make sure that never happens, but gave no details".
Wounded In South Africa Plane Crash
A spokesman for Martin's Air also said it did not know what had prompted the incident. A charter plane lays in a field in Pretoria, South Africa, Tuesday July 10, 2018.
Several dead after train derails in Turkey
Over the past few years, Turkish cities have been building high-speed rail lines to replace the country's ageing network. Tekirdag governor Mehmet Ceyhan said the area where the derailment happened was muddy and hard to reach.
Ibrahimovic Tips Sweden For World Cup Glory
Russian Federation will try to take it all the way, I think. Russian Federation surprised me by beating Spain. You don't get afraid when you see this team.
Some Conservative Party lawmakers warned they would not tolerate a betrayal of Brexit.
I think the changes in the British negotiating position on Brexit over the last few days are welcome - they are not the finished article. However, the Environment Secretary later insisted he would not be leaving the Cabinet.
"Now there is chaos", the paper said in its editorial.
Creating a political storm when he compared European Union efforts to create a superstate to Hitler's attempt to rule the continent, saying: "Napoleon, Hitler, various people tried this out, and it ends tragically".
In the June 23, 2016 referendum, 17.4 million voters, or 51.9 percent, backed leaving the European Union, while 16.1 million voters, or 48.1 percent, backed staying. Finally, there was the most likely outcome: that the meeting would produce a fudge which pushed most decisions further down the road.
He told the programme: "What we are trying to do is not open revolt but we are trying to tell the Prime Minister and the Cabinet that we have got real concerns about where this is going".
"If people don't like this proposal, what is their alternative?"
European Commission president Jean-Claude Juncker promised that the EU would "continue to negotiate in good faith", while his chief spokesman said Mr Davis' departure would not affect the approach of Brussels, saying: "We are here to work".
By the time the Cabinet members emerged from their country house retreat, it looked like May had managed to combine option one with a large helping of fudge, which seemed to be quite a coup for a prime minister not used to success.