Buenos Aires-born Maxima had a close relationship with her youngest sister, who was bridesmaid at her wedding to then Crown Prince Willem-Alexander in 2002.
A spokesperson for the Dutch government confirmed the news to La Nación: "We can confirm that Inés Zorreguieta, sister of Queen Maxima of the Netherlands, died on Wednesday night". Zorreguieta reportedly suffered from depression and was seeking psychological help.
Queen Maxima, of the Dutch Royal Family, has made a decision to cancel her public appearances in the coming days in light of the bad news that her sister has passed away.
Queen Maxima of the Netherlands. She was godmother to the royal couple's youngest daughter, Princess Ariane, 11. "It is intensely sad and heartbreaking news that can hardly be comprehended for those who stay behind", Dutch Prime Minister Mark Rutte said.
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She was a civil servant who had been working for the Argentinian government since 2016, in an office that oversees social policies. "And I trust that they will get the peace and space for that".
Máxima said in a reaction that she is "very shocked and very upset" by the news, the RVD said. She has since canceled her forthcoming engagements including a state visit to Estonia, Latvia and Lithuania next week.
Inés and Maxima's father, Jorge Zorreguieta, died previous year at the age of 89.